Osteoarthritis

Complications of lateral plate fixation compared with tension band wiring and pin or lag screw fixation for calcaneoquartal arthrodesis. Treatment of proximal intertarsal subluxation occurring secondary to non-traumatic plantar tarsal ligament disruption

Authors: Barnes DC, Knudsen CS, Gosling M, McKee M, Whitelock RG, Arthurs GI, Ness MG, Radke H, Langley-Hobbs SJ

Journal: VCOT

Objective: To compare complication rates and the outcomes of these complications after lateral plate fixation with figure-of-eight tension-band-wire and pin or lag screw fixation for arthrodesis of the calcaneo-quartal joint, following non-traumatic disruption of the plantar tarsal ligament in dogs. Methods: Data were collected retrospectively from five UK referral centres. Diplomate specialists and their residents performed all procedures. Referring veterinarians were contacted for long-term follow-up. Results: Seventy-four procedures were undertaken in 61 dogs.

Category: Arthritis - Fracture Fixation and Implants - Hock - Osteoarthritis - Tendon and Ligament Injuries - Trauma

Anti-inflammatory response of dietary vitamin E and its effects on pain and joint structures during early stages of surgically induced osteoarthritis in dogs.

Authors: Rhouma M, de Oliveira El Warrak A, Troncy E, Beaudry F, Chorfi Y.

Journal: Can J Vet Res

There is evidence that vitamin E (VE) has anti-inflammatory and analgesic properties in human osteoarthritis (OA). This double-blinded and randomized pilot study used a broad spectrum of clinical and laboratory parameters to investigate whether such beneficial effects could be detected in a canine experimental OA model. Dogs were divided into 2 groups: control (n = 8), which received a placebo, and test group (n = 7), which received 400 IU/animal per day of VE for 55 d, starting the day after transection of the cranial cruciate ligament.

Category: Arthritis - Biologics - Osteoarthritis - Pain Management

Prospective trial of autologous conditioned plasma versus hyaluronan plus corticosteroid for elbow osteoarthritis in dogs.

Authors: Franklin SP, Cook JL.

Journal: Can Vet J

This prospective, randomized, double-blinded trial compared outcomes in dogs with bilateral elbow osteoarthritis (OA) treated with hyaluronan plus methylprednisolone (HA + S) or autologous conditioned plasma (ACP(®); Arthrex). An investigator blinded to the treatments graded lameness (0-4) before and 6 months after a single injection with either HA + S or ACP. Clients were blinded to treatment and completed a validated survey before and 1, 6, 12, and 24 weeks after injection. Ten dogs (5 per group) completed all parts of the study.

Category: Arthritis - Biologics - Elbow - Osteoarthritis - Pain Management

Prospective trial of autologous conditioned plasma versus hyaluronan plus corticosteroid for elbow osteoarthritis in dogs.

Authors: Franklin SP, Cook JL.

Journal: Can Vet J

Category: Arthritis - Biologics - Elbow - Osteoarthritis - Pain Management

A randomized controlled trial of the efficacy of autologous platelet therapy for the treatment of osteoarthritis in dogs.

Authors: Fahie MA, Ortolano GA, Guercio V, Schaffer JA, Johnston G, Au J, Hettlich BA, Phillips T, Allen MJ, Bertone AL.

Journal: JAVMA

Objective-To determine efficacy of a single intra-articular injection of an autologous platelet concentrate for treatment of osteoarthritis in dogs. Design-Randomized, controlled, 2-center clinical trial. Animals-20 client-owned dogs with osteoarthritis involving a single joint. Procedures-Dogs were randomly assigned to a treatment or control group. In all dogs, severity of lameness and pain was scored by owners with the Hudson visual analog scale and the University of Pennsylvania Canine Brief Pain Inventory, respectively, and peak vertical force (PVF) was determined with a force platform.

Category: Arthritis - Biologics - Osteoarthritis - Pain Management

Arthroscopic features of primary and concomitant flexor enthesopathy in the canine elbow.

Authors: de Bakker E, Samoy Y, Coppieters E, Mosselmans L, Van Ryssen B.

Journal: VCOT

Objectives: To investigate the possibilities and limitations of arthroscopy to detect flexor enthesopathy in dogs and to distinguish the primary from the concomitant form. Materials and methods: Fifty dogs (n = 94 elbow joints) were prospectively studied: dogs with primary flexor enthesopathy (n = 29), concomitant flexor enthesopathy (n = 36), elbow dysplasia (n = 18), and normal elbow joints (n = 11). All dogs underwent an arthroscopic examination of one or both elbow joints.

Category: Arthritis - Arthroscopy - Elbow - Imaging - Osteoarthritis - Tendon and Ligament Injuries

In vitro biomechanical comparison of load to failure testing of a canine unconstrained medial compartment elbow arthroplasty system and normal canine thoracic limbs.

Authors: Smith ZF, Wendelburg KL, Tepic S, Stover SM, Garcia-Nolen T, Stearns PB, Hayashi K.

Journal: VCOT

Elbow dysplasia, primarily affecting the medial compartment, is the most common cause of lameness in the thoracic limb. Elbow arthroplasty is an option for end stage or severely affected patients. The purpose of this study was to compare ex vivo axial load to failure of an implanted novel elbow arthroplasty system to control limbs. The partial arthroplasty is a medial compartmental, unconstrained system, intended to allow conversion to total arthroplasty. We hypothesized that there would not be any significant difference between implanted and controlled limbs when loaded to failure.

Category: Arthritis - Elbow - Fracture Fixation and Implants - Osteoarthritis - Pain Management

The use of planar bone scintigraphy and HiSPECT for diagnosis of primary and concomitant flexor enthesopathy in the canine elbow.

Authors: de Bakker E, Peremans K, Vermeire S, Vandermeulen E, Dobbeleir A, Dik KJ, Gielen I, Saunders JH, Van Ryssen B

Journal: VCOT

Objective: To investigate the possibilities and limitations of planar bone scintigraphy and high resolution single photon emission computed tomography (HiSPECT) to diagnose flexor enthesopathy and to distinguish primary flexor enthesopathy from the concomitant form. Materials and methods: A prospective study of 46 dogs with primary flexor enthesopathy, concomitant flexor enthesopathy, medial coronoid disease, and normal elbows was performed. All dogs underwent planar bone scintigraphy and HiSPECT imaging.

Category: Arthritis - Elbow - Imaging - Osteoarthritis - Pain Management - Rehabilitation - Tendon and Ligament Injuries

Use of an owner questionnaire to evaluate long-term surgical outcome and chronic pain after cranial cruciate ligament repair in dogs: 253 cases (2004-2006).

Authors: Mölsä SH, Hielm-Björkman AK, Laitinen-Vapaavuori OM.

Journal: JAVMA

Objective-To evaluate, by means of an owner questionnaire, long-term outcome and prevalence of chronic pain after cranial cruciate ligament (CCL) surgery in dogs. Design-Retrospective case series. Animals-253 dogs with surgically treated CCL rupture. Procedures-Data from surgical records of dogs that underwent surgical repair of CCL between 2004 and 2006 were reviewed.

Category: Arthritis - Knee - Osteoarthritis - Pain Management

In vitro effects of meloxicam on metabolism in articular chondrocytes from dogs with naturally occurring osteoarthritis.

Authors: Budsberg SC, Stoker AM, Johnston SA, Liska W, Reno LR, Cook JL.

Journal: AJVR

Objective-To assess effects of in vitro meloxicam exposure on metabolism in articular chondrocytes from dogs with naturally occurring osteoarthritis Sample-Femoral head cartilage from 16 dogs undergoing total hip replacement Procedures-Articular cartilage samples were obtained. Tissue sulfated glycosaminoglycan (SGAG), collagen, and DNA concentrations were measured. Collagen, SGAG, chondroitin sulfate 846, NO, prostaglandin E2 (PGE2), and matrix metalloproteinase (MMP)-2, MMP-3, MMP-9, and MMP-13 concentrations in culture medium were analyzed.

Category: Arthritis - Biologics - Osteoarthritis - Pain Management