Osteoarthritis

Osteochondrosis (OC) is common in large-breed dogs. According to the breeding guidelines of the Swiss kennel clubs, the shoulder joints are included in the radiographic screening for joint diseases in the Greater Swiss Mountain dog (GSMD) and the Border Collie (BC) since 1993 and 2003, respectively.

The aim of this study was to estimate the overall prevalence of humeral head OC in these 2 breeds in Switzerland based on the data of the Swiss National Dysplasia Committees. All radiographs were re-evaluated to assess single radiographic changes.

BACKGROUND: This study evaluated the effectiveness and safety of grapiprant for treatment of pain in dogs with osteoarthritis (OA).

HYPOTHESIS/OBJECTIVES: Grapiprant will relieve pain as measured by the owner's and veterinarian's evaluation of pain in dogs with OA. Another objective was evaluation of the safety of grapiprant.

ANIMALS: Two hundred and eighty-five client-owned dogs with OA were enrolled and treated with grapiprant or placebo with 262 cases (N = 131 in each group) evaluable for the effectiveness analysis.

OBJECTIVE: To evaluate the safety and efficacy of an intra-articular injection of autologous protein solution (APS) for treatment of canine osteoarthritis (OA).

STUDY DESIGN: Prospective, randomized, blinded, placebo-controlled pilot clinical trial.

ANIMALS: Client-owned dogs with single limb lameness because of OA in a stifle or elbow joint (n=21).

Category: Osteoarthritis

Adenosine triphosphate has been shown to stimulate nociceptive nerve terminals in joints. Elevated synovial fluid adenosine triphosphate concentrations as well as a correlation between synovial fluid adenosine triphosphate concentrations and osteoarthritic knee pain has been demonstrated in humans, but not yet in dogs.

OBJECTIVE: To record and categorize the outcome measures used in dogs with naturally occurring osteoarthritis (OA) by systematically reviewing the peer reviewed publications on OA in dogs.

STUDY DESIGN: Systematic literature review.

OBJECTIVE: The study aims were to evaluate the effects of radial shock wave therapy (RSWT) in dogs with hip osteoarthritis (OA) using clinical assessment and kinetic analysis.

Category: Hip - Osteoarthritis

OBJECTIVE: To describe the radiographic, computed tomography (CT), and arthroscopic findings in the elbow of dogs admitted for elbow lameness after previous arthroscopic treatment of medial coronoid disease (MCD).

STUDY DESIGN: Retrospective case series.

ANIMALS: Client-owned dogs (n = 25) admitted for elbow lameness after arthroscopic treatment.

OBJECTIVE:  To report synovial fluid lactate concentrations in normal and pathological canine joints.

STUDY DESIGN:  Controlled, prospective study.

OBJECTIVES:  To describe the use of the Fixin locking plate system for stifle arthrodesis in dogs and to retrospectively report the clinical and radiographic outcomes in six cases.

Category: Knee - Osteoarthritis

AIM:  To test whether intra-articular injection of porcine adipose-derived stem cells (ADSCs) can treat canine osteoarthritis (OA).