Diagnosis of Streptococcus canis periprosthetic joint infection: the utility of next-generation sequencing

Arthroplast Today. 2017 Nov 3;4(1):20-23. eCollection 2018 Mar.

A 62-year-old man who had undergone a primary knee arthroplasty 3 years earlier, presented to the emergency department with an infected prosthesis. He underwent prosthesis resection.

All cultures failed to identify the infecting organism. Analysis of the intraoperative samples by next-generation sequencing revealed Streptococcus canis (an organism that resides in the oral cavity of dogs).

It was later discovered that the patient had sustained a dog scratch injury several days earlier. The patient reports that his dog had licked the scratch.

Treatment was delivered based on the sensitivity of S. canis, and the patient has since undergone reimplantation arthroplasty.

KEYWORDS: Culture negative; Hip arthroplasty; Knee arthroplasty; Next-generation sequencing; Periprosthetic joint infection

Small animal: